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Metabolomics can provide valuable assessment of metabolic effects of specific disease treatments on pathogenic factors [22]

A normal uncompressed thinned skull preparation was performed on the contralateral hemisphere as a control (top)

An ideal linker should: Different types of linkers can significantly affect the pharmacokinetics (PK), biodistribution, therapeutic effects, and safety of ADCs

The N-terminal periplasmic domains also interact with the components of the cytoplasmic membrane-embedded platform of the secretion machinery, to promote channel opening, cargo docking, and subsequent release 26,27

In using fats to produce energy, the excess fatty acids are diverted to make molecules called ketones or ketone bodies

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